We are reverse-engineers. Our goal is to unravel the intricate mechanisms by which key regulatory components govern the complex gene regulation network. To accomplish this, we employ a combination of high-throughput biochemistry, bioinformatics data analysis, and machine learning to examine molecular mechanisms at a systems level.

With a primary focus on developing large-scale experimental methods and novel data analytic toolchains, we strive to gain a more profound understanding of the quantitative nature of post-transcriptional gene regulation. By utilizing single-molecule-level measurements of various RNA states—including RNA modifications, chemical adducts, and poly(A) tail lengths—at a transcriptome scale, we can uncover the hidden rules shaped by multiple cis-regulatory factors.

We are currently seeking motivated graduate students and postdocs to join our collaborative research efforts in this exciting field (more info)!

Our lab is affiliated with the School of Biological Sciences and the Interdisciplinary Program in Bioinformatics at Seoul National University. Currently, our group’s research is supported by funding from the Center for RNA Research in the Institute for Basic Science (IBS) and the National Research Foundation of Korea’s Excellent Young Researcher program.

News

Jan 29, 2024

Jayoung has been selected as the latest recipient of the Woosan Scholarship.

Dec 1, 2023

Junsoo has been selected as a new JW Foundation Basic Scientist Scholarship recipient.

Nov 15, 2023

Heeseung won the Best Poster Award at the BIOINFO 2023 conference.

Oct 27, 2023

Junsoo was awarded the Outstanding Oral Presentation Award at the Annual Meeting of the Microbiological Society of Korea.

Aug 11, 2023

Hyeshik illustrates the early days of the Korean Python community and Python 2 in his keynote at PyCon Korea 2023.

Nov 22, 2022

The Youlchon AI for All Fellowship has selected Junsoo as a new scholar to be supported.

Nov 11, 2022

We have published two papers describing the detailed procedure to analyze viral transcriptomes and its application to human cytomegalovirus (HCMV) long noncoding RNAs.

Jul 14, 2022

The 3·1 scholarship has chosen Junsoo as its newest recipient.

Nov 18, 2021

Hyeshik explains why computer scientists should be interested in biology in the Samsung Software Developer Conference 2021.

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